Lynx Platform

The extraction of useful knowledge from voluminous data produced by high-throughput genomics presents a significant challenge to the scientific community. Efficient mining of this data for the needs of biomedical research critically depends on seamless integration of clinical, genomic and experimental information with prior knowledge about genotype-phenotype relationships accumulated in a plethora of publicly available databases. Furthermore, such experimental data should be accessible to a variety of algorithms and analytical pipelines that drive computational analysis and data mining.

To address these challenges we are developing Lynx -- a scalable computational platform based on cross-cutting requirements from multiple scientific groups for data integration, management and analysis. The goal of Lynx is to provide an end-to-end support for the analytical needs of various translational projects.

 Our Team 

Lynx platform is being developed by the Bioinformatics group at Prof. Gilliam's Lab at the Human Genetics Department, University of Chicago
(PI - N. Maltsev, Technical Lead - D. Sulakhe).
Natalia Maltsev (PI)

My major scientific interest is the development of the approaches for representation and analysis of complex biological systems and how these approaches can be applied to the discovery of the molecular mechanisms contributing to complex heritable disorders.

T. Conrad Gilliam
Dean for Research and Graduate Education, Biological Sciences Division
Marjorie I. and Bernard A. Mitchell Professor, Department of Human Genetics
Senior Fellow, Computation Institute
Pritzker Fellow, University of Chicago and the Pritzker School of Medicine
Gilliam Lab Director

Dina Sulakhe

Director, Clinical and Translational Research Informatics

Center for Research Informatics (CRI), BSD
Lynx Project Architect and Technical Lead

Bingqing Xie

Postdoctoral Researcher

Mark D'Souza

Senior Bioinformatics Analyst

Andrew Taylor

Application Developer

Sandy Balasubramanian

Bioinformatics Researcher


Barnett Glickfeld Ph.D
Associate Professor, Northern Illinois University


Jinbo Xu - Associate Professor of Toyota Technological Institute at Chicago

Sheng Wang - Research Fellow, Toyota Technological Institute at Chicago

Inna Dubchak - Senior Scientist, Lawrence Berkeley National Laboratory

Alex Paciorkowski - Assistant Professor of Neurology, Pediatrics, and Biomedical Genetics at the University of Rochester Medical Center

Ghayda Mirzaa - Acting Instructor of Pediatrics at the University of Washington

Somaye Hashemifar - Graduate Student, Toyota Technological Institute at Chicago

Sheng Wang - Post Doctoral Scholar, Toyota Technological Institute at Chicago

 Former Members  

Paul Dave - Director of user services, Computation Institute
Daniela Börnigen - Sr. Postdoctoral Researcher
Eduardo Berrocal - Applications Programmer
Bo Feng - Graduate Student, Illinois Institute of Technology
Bhadrachalam Chitturi - Visiting Researcher, Amrita School of Engineering

 Contact Us  

Scientific Collaborations: Natalia Maltsev
Platform and Technology: Dina Sulakhe